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Topic: Herpesviridae

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Herpesviridae

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Herpesviridae

/download.spark?ID=1149176&aBID=147929

Family

Strand Type

Capsid Symmetry

Envelope or Naked Virion

Diameter (nm.)

Disease Example

Herpesviridae

Double

Icosahedral

Envelope

150-300

Cold sores, genital herpes, chickenpox, shingles, infectious mononucleosis

 


cold sore.jpg Cold sores

Genital herpes.png  Genital herpes

Shingles.jpg  Shingles

infectious mononucleosis.jpg Infectious mononucleosis

Human Herpesvirus (HHV) classification
TypeSynonymSubfamilyPrimary Target CellPathophysiologySite of LatencyMeans of Spread
HHV‑1Herpes simplex virus-1 (HSV-1)α (Alpha)MucoepithelialOral and/or genital herpes (predominantly orofacial), as well as other herpes simplex infectionsNeuronClose contact (oral or sexually transmitted infection)
HHV-2Herpes simplex virus-2 (HSV-2)αMucoepithelialOral and/or genital herpes (predominantly genital), as well as other herpes simplex infectionsNeuronClose contact (sexually transmitted disease)
HHV-3Varicella zoster virus (VZV)αMucoepithelialChickenpox and shinglesNeuronRespiratory and close contact (including sexually transmitted disease)
HHV-4Epstein-Barr virus (EBV), lymphocryptovirusγ (Gamma)B cells and epithelial cellsInfectious mononucleosisBurkitt's lymphomaCNS lymphoma in AIDS patients,
post-transplant lymphoproliferative syndrome (PTLD), nasopharyngeal carcinoma, HIV-associated hairy leukoplakia
B cellClose contact, transfusions, tissue transplant, and congenital
HHV-5Cytomegalovirus (CMV)β (Beta)Monocytelymphocyte, andepithelial cellsInfectious mononucleosis-like syndrome,[10] retinitis, etc.Monocyte, lymphocyte, and ?Saliva
HHV-6Roseolovirus, Herpes lymphotropic virusβT cells and ?Sixth disease (roseola infantum or exanthem subitum)T cells and ?Respiratory and close contact?
HHV-7Pityriasis RoseaβT cells and ? ? (roseola infantum or exanthem subitum)T cells and ? ?
HHV-8Kaposi's sarcoma-associated herpesvirus
(KSHV), a type of rhadinovirus
γLymphocyte and other cellsKaposi's sarcomaprimary effusion lymphoma, some types of multicentricCastleman's diseaseB cellClose contact (sexual), saliva?

http://en.wikipedia.org/wiki/Herpesviridae



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